Automatic Vial Filling Machine

Spray/Fluid Dispensing Filling Machine: Precision System for Metered-Dose and Liquid Pharmaceutical Sprays

Introducing our specialized Spray/Fluid Dispensing Filling Machine, a precision-engineered automatic vial filling machine designed for the unique challenges of packaging nasal sprays, oral sprays, inhalers, and other metered-dose or liquid spray products. This advanced system accurately fills both the liquid formulation and, when required, inserts and crimps the mechanical spray pump into vials, bottles, or canisters. As a critical component in a comprehensive vial filling line, this machine ensures consistent shot weight, precise fill volume, and secure pump attachment, making it an essential vial filling and sealing machine for respiratory, otic, ophthalmic, and topical drug delivery systems.

capping part   The capping part of the pharmaceutical spray filling machine is designed to securely apply spray pumps or actuators with precise, repeatable torque control. After filling, each bottle is accurately positioned in the capping station, where the system automatically aligns and presses the spray cap into place without damaging the pump assembly. The mechanism maintains stable, vibration-free motion to protect container integrity and ensure a tight, leak-proof seal. Compatible with various spray pump designs, the capping module uses GMP-compliant materials and offers easy adjustment for different bottle sizes. This section guarantees consistent sealing quality essential for reliable spray performance and pharmaceutical-grade safety.

filling part   The filling part of the pharmaceutical spray filling machine is engineered for precise and contamination-free dosing of liquid formulations into spray bottles or vials. The filling nozzles deliver accurate, repeatable volumes using servo-controlled metering, ensuring stable flow and preventing foaming or dripping during operation. Designed to accommodate low-viscosity and sensitive pharmaceutical solutions, the system maintains laminar filling to protect product integrity. Integrated sensors monitor each container’s position to ensure correct alignment before dispensing, while GMP-compliant contact materials guarantee a hygienic and easily sanitized filling environment. This module provides the accuracy, consistency, and reliability essential for high-quality spray product manufacturing.

Engineered for Accuracy in Spray Device Assembly

Unlike standard liquid fillers, this machine integrates precision volumetric filling with automated pump handling and crimping/capping stations. It is designed to handle the viscosity range of spray formulations—from aqueous solutions to suspensions—while maintaining accuracy within ±1% for critical metered doses. The system automatically orients, places, and secures spray pumps, actuator buttons, or other dispensing closures onto the filled containers, completing the primary packaging process in one seamless operation. This integrated functionality makes it a cornerstone automatic vial filling machine for products where the delivery device is integral to the drug product performance.

Seamless Integration into Aseptic & Controlled Lines

This machine is built for integration within a validated vial filling line, connecting effortlessly with upstream components like vial washers and depyrogenation tunnels, and downstream systems such as labelers and cartoners. Its design supports cleanroom installation, with options for laminar airflow hoods or isolator interfaces to meet stringent requirements for sterile nasal or ophthalmic sprays. As a specialized vial filling and sealing machine, it ensures the critical interface between the container and the spray mechanism is assembled under controlled conditions, guaranteeing dose uniformity and container closure integrity as per pharmacopeial standards.

Core Features & Technical Advantages

• Dual-Function Precision: Combines high-accuracy liquid filling (peristaltic or piston pump) with automated spray pump insertion, seating, and crimping.

• Metered Dose Consistency: Advanced weight or volume check systems verify each dispensed dose, ensuring compliance with strict pharmacopeial requirements for sprays and inhalers.

• Flexible Platform: Configurable to handle various container types (glass/PET vials, HDPE bottles) and pump designs (nasal, oral, topical sprays).

• Aseptic Design Options: Constructed with 316L stainless steel, featuring CIP/SIP capabilities and a design compatible with Grade A/B cleanroom environments for sterile product filling.

• Data Integrity & Control: PLC-based system with HMI provides recipe management, comprehensive machine monitoring, and 21 CFR Part 11-compliant data logging for full batch traceability.

Ideal Applications

• Nasal Sprays: Steroid sprays, saline solutions, decongestants, and vaccine delivery systems.

• Oral & Buccal Sprays: Systemic drug delivery sprays, pain management formulations.

• Ophthalmic & Otic Sprays: Sterile eye washes and ear drop sprays.

• Topical & Dermatological Sprays: Antiseptics, local anesthetics, and wound care sprays.

• Medical Device Kits: Pre-filled spray components for surgical or first-aid kits.

Your Partner in Advanced Drug Delivery Packaging

We provide end-to-end partnership, from initial application testing with your specific container and pump combination to full installation, qualification (IQ/OQ/PQ), and operator training. We ensure this specialized automatic vial filling machine integrates perfectly into your vial filling line, delivering the precision and reliability required for complex drug-device combination products.