Pharmaceutical Vial Filling Machine

INTRODUCTION

High-Precision Vial Filling Machine: Engineered for Pharmaceutical Excellence

Introducing our High-Precision Vial Filling Machine, a versatile and robust pharmaceutical vial filling machine engineered to meet the stringent demands of modern sterile and non-sterile production. Designed for maximum flexibility, this system excels as a dedicated small vial filling machine for critical applications like vaccines, injectables, and ophthalmics, while its modular architecture allows it to be seamlessly integrated into a complete vial filling and sealing machine for end-to-end automation. Built with uncompromising quality for cleanroom environments, it delivers exceptional accuracy, speed, and reliability for pharmaceutical, biotech, and diagnostic manufacturers worldwide.

capping part

The capping part of the small vial filling machine is designed to ensure secure, consistent sealing for pharmaceutical vials following the filling process. Each vial is accurately positioned in the capping station, where caps are automatically placed and tightened with precise torque control. The stable capping mechanism minimizes vibration and vial movement, preventing breakage and ensuring reliable closure integrity. Compatible with various vial sizes and cap types, the system is constructed from GMP-compliant materials and supports smooth, continuous operation. This capping module delivers uniform sealing quality, reduces the risk of leakage, and meets the stringent requirements of pharmaceutical production environments.

filling part

The filling part of the small vial filling machine is engineered to provide accurate, stable, and repeatable liquid dosing for pharmaceutical applications. Vials are precisely indexed into position, where high-precision filling nozzles dispense the preset volume with minimal splashing or foaming. The system supports a wide range of liquid formulations and maintains consistent fill accuracy through controlled flow and synchronized operation. Anti-drip nozzle design and smooth bottle handling help prevent product loss and contamination. Manufactured with GMP-compliant contact materials, the filling module ensures hygienic operation and reliable performance for modern small-vial production lines.

filling part

washing machine

The small vial filling machine can be optionally equipped with a washing machine based on customer requirements. This flexible configuration allows vials to undergo thorough internal and external cleaning before entering the filling stage, ensuring higher hygiene and compliance with pharmaceutical standards. The washing module can be tailored to different vial sizes and production speeds, providing efficient, contamination-free preparation for sensitive liquid formulations. By integrating this option, manufacturers can achieve a fully automated wash–fill–cap process while maintaining GMP-compliant cleanliness throughout the production line.

Core Engineered for Critical Pharmaceutical Processes

This machine is designed from the ground up as a true pharmaceutical vial filling machine. It incorporates a servo-driven, peristaltic pump filling system that ensures precise, contact-free liquid dispensing with accuracy within ±0.5%, essential for high-value biologics and potent compounds. The system is constructed with 316L stainless steel and pharmaceutical-grade components, supporting full Clean-in-Place (CIP) and Steam-in-Place (SIP) protocols. Its hygienic design minimizes dead legs and features smooth, polished surfaces, making it the ideal small vial filling machine for aseptic processing lines requiring compliance with global cGMP and Annex 1 guidelines.

Modular Design for Seamless Integration and Expansion

Understanding the need for scalable solutions, this platform is inherently modular. As a standalone filler, it operates as a high-speed small vial filling machine. However, its true power is realized when integrated with additional modules. It can be directly coupled with automatic stoppering, screw-capping, or snap-capping stations to create a unified vial filling and sealing machine. This integrated approach eliminates transfer points, reduces contamination risk, and optimizes floor space. The machine easily connects within a larger vial filling line, interfacing with washers, depyrogenation tunnels, and lyophilizers for sterile products, or with unscramblers and labelers for non-sterile lines.

Key Features and Technical Specification

Ultra-Precise Filling Technology: Utilizes peristaltic pump or time-pressure filling for exceptional accuracy (±0.5%) across a wide volume range (0.1mL to 500mL), ideal for sensitive formulations.
Gentle Vial Handling: A proprietary conveyor and gripper system ensures smooth, precise vial transport without tipping or stress, crucial for fragile glass containers.
Advanced Control & Data Integrity: Features a 21 CFR Part 11-compliant PLC with a large HMI touchscreen for recipe management, electronic batch records, and comprehensive audit trails.
Rapid Changeover: Tool-less adjustments and quick-change parts assemblies allow for fast switchovers between different vial sizes and fill volumes, maximizing uptime.
Containment Options: Available with integrated containment solutions (e.g., split valve technology, isolator interfaces) for the safe handling of highly potent active pharmaceutical ingredients (HPAPIs).

Ideal Applications

Sterile Injectables: Vaccines, monoclonal antibodies, antibiotics, and cytotoxic drugs.
Ophthalmic & Otic Solutions: Eye drops, ear drops, and sterile irrigations.
Diagnostic & Laboratory Reagents: Buffers, calibrators, and assay components.
Advanced Therapies: Cell and gene therapy vectors, cryopreservation solutions.

Your Partner in Pharmaceutical Manufacturing

We provide more than a machine; we offer a partnership. Our support includes comprehensive process analysis, factory acceptance testing (FAT), on-site installation and qualification (IQ/OQ), and ongoing technical service. Our experts ensure your pharmaceutical vial filling machine is optimized for your specific product and validated to meet all regulatory requirements.

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