Pretreatment system

Multi-effect water distiller:

The preparation system of water for injection is a key GMP system. The multi-effect distilled water machine is the key equipment in the widely used water for injection preparation system. High temperature and high pressure operation ensures stable production of pyrogen free water for injection. Distilled water produced * Current US Pharmacopoeia, European Pharmacopoeia, Japanese Pharmacopoeia and Chinese Pharmacopoeia requirements for water for injection.

How it works:

The process is as follows: raw material water is heated by industrial steam in the primary effect preheater, and each effect preheater is heated by secondary steam after entering; The condenser is heated by secondary steam and distilled water; Then, through the water separation device at the top of the evaporator, it is evenly distributed into the evaporation tube, and the film-like water flow is formed in the evaporation tube. The thin water quickly evaporates, producing secondary steam; The raw material water that has not been evaporated is transported to the next effect, as the raw material water of the secondary effect evaporator, and the subsequent effects are similar, the unevaporated into the next effect, until the last effect has not been evaporated, will be discharged as condensate water; The evaporated raw material water, now the secondary steam, continues to spiral up in the evaporator, and enters the pure steam pipeline through the special separation device in the middle and upper part, as a secondary heat source; The secondary steam condenses into distilled water after the heat is absorbed in the secondary effect. The process of each effect is similar, the distilled water of each effect and the secondary steam of the final effect are collected by the condenser, and after heat exchange with cooling water and raw water, cooled into distilled water; After the online detection of electrical conductivity, qualified distilled water is output as water for injection, and unqualified distilled water will be discharged.

The secondary steam converted into raw water is clean steam, which goes through three separations: after entering the evaporator at the beginning, it flows down the tube and evaporates at the same time, which is the first separation; The evaporated raw material water (secondary steam) returns 180 degrees at the lower end of the evaporator, and the impurities are separated to the lower part under the action of gravity, which is the second separation; The evaporated raw material water, that is, the secondary steam, continues to spiral up in the evaporator to the special separation unit in the middle and upper part for a third separation. The cooling water only passes through the condenser to cool the distilled water produced by each effect and the secondary steam of the final effect. The industrial steam heats the raw water in the most efficient evaporator and preheater, and the heat is absorbed and discharged as condensate water. In the condenser, there is a part of the gas that cannot condense into water, which is called non-condensable gas, and this part of the gas will be removed by the discharge device installed in the upper part of the condenser. Depending on the model, a continuous discharge device for non-condensing gas may also be provided on each effect evaporator.

Multi-effect distilled water machine supply features

1, structural material: with distilled water, secondary pure steam in contact with the pressure vessel body, pipe using 316L, sealing material using PTFE. Other materials including the rack are made of 304 material.

2, three-stage separation device: the raw material water entering the equipment through downliquid membrane evaporation, gravity separation, special separation device three-stage separation.

3, electrochemical polishing: stainless steel surface electrochemical polishing, to ensure the quality of water for injection production, improve the service life of equipment.

4, double tube plate design: external preheater, condenser and efficiency evaporator are double tube plate design, in line with the requirements of cGMP, effectively eliminate the possibility of low health level media pollution system.

5, the heat exchange tube adopts high-quality seamless pipe: seamless pipe has better strength and durability, to ensure that in the process of processing, welding, expansion and operation of the thermal expansion and contraction process to remain in good condition, to avoid any industrial steam, raw water and cooling water leakage into clean distilled water, secondary steam side.

6, three-dimensional bending: in the pipeline as far as possible to use stainless steel pipe directly draw bending pipe, avoid welding.

7, the use of automatic welding: the connection of pipelines and parts, as far as possible to use automatic argon protection track welding, to ensure the quality of welding.

8, heat insulation: evaporator and preheater are made of non-chlorine, non-asbestos mineral wool insulation layer, and covered with stainless steel cladding.

9, only economic material water pretreatment: no need for expensive purified water equipment, raw water only needs to be deionized water or reverse osmosis water with electrical conductivity less than 5μS/cm.

10, economic and energy saving: Because the secondary steam is used step by step in each effect, the utilization rate of industrial steam is very high, and it has obvious energy-saving effect. With the increase of evaporator efficiency, this energy-saving effect is more obvious. At the same time, the amount of cooling water also decreased significantly with the increase of the effect number.

11, control system: the use of PLC automatic control technology to achieve different control requirements of customers. From the basic distilled water quality judgment and distribution, to more advanced such as continuous adjustment of each medium, linkage with storage systems, hierarchical cryptographic control and even control of evaporation changes, it can be said to be meticulous.

12, paperless record: the use of paperless record, the true record of production.

13, the whole machine performance factory test: in the whole machine test workshop, in accordance with the determined procedures, simulate the actual working environment, the whole machine test

Multiple-Effect Distilled Water Machine: Pharmaceutical-Grade Water Purification Excellence

Achieve the highest standards of water purity with our advanced Multiple-Effect Distilled Water Machine, an integrated water purification solution designed specifically for pharmaceutical, biotechnology, and healthcare applications. This sophisticated system begins with our comprehensive pretreatment system, specifically engineered to remove contaminants and protect downstream components, ensuring consistent production of pyrogen-free distilled water that exceeds international pharmacopeia standards.

Our complete line of pre treatment solutions forms the critical first stage in the distillation process, effectively eliminating particulates, chlorine, organic matter, and other impurities that could compromise final water quality. As specialized pretreatment equipment, these systems are custom-configured to handle varying feed water conditions, providing reliable protection for the multiple-effect distillation units that follow.

Key Features & Benefits:

• Advanced Multi-Effect Distillation Technology
The heart of the system utilizes energy-efficient multiple-effect distillation, where vapor from one chamber serves as the heat source for the next. This innovative design reduces energy consumption by up to 70% compared to single-effect stills while producing high-purity Water for Injection (WFI) quality output.

• Comprehensive Pretreatment System
Our integrated pretreatment system includes multi-media filtration, activated carbon adsorption, and reverse osmosis modules that collectively remove up to 99% of feed water contaminants. This robust pretreatment equipment ensures optimal feed water quality, protecting distillation components from scaling and fouling.

• Customized Pre Treatment Solutions
We provide tailored pre treatment solutions based on your specific water source analysis and production requirements. Our flexible pretreatment system can be configured with various filtration media, softening units, and membrane technologies to address unique water challenges.

• Automated Operation & Monitoring
The system features a sophisticated PLC control with touchscreen interface that monitors all critical parameters including conductivity, TOC, flow rates, and temperatures. Automated controls and data logging ensure consistent performance and simplify validation processes.

• Energy-Efficient Design
The multiple-effect configuration significantly reduces steam and cooling water requirements compared to traditional distillation methods. Heat recovery systems within the pretreatment equipment further enhance overall energy efficiency, lowering operational costs.

Applications:

• Pharmaceutical Water for Injection (WFI) production

• Biotechnology and vaccine manufacturing

• Parenteral and intravenous solutions

• Laboratory research facilities

• Medical device manufacturing

Our Multiple-Effect Distilled Water Machine represents the pinnacle of water purification technology, combining energy-efficient distillation with robust pretreatment equipment to deliver uncompromising water quality. The integrated pretreatment system ensures consistent feed water conditions, while our customized pre treatment solutions extend equipment lifespan and reduce maintenance requirements. This complete system provides reliable, validated performance for the most critical pharmaceutical water applications.

Contact us today to discuss your water purification needs. Our technical team will design the perfect pretreatment system and distillation solution to meet your specific production requirements and quality standards.